446-35-5 | 2,4-Difluoronitrobenzene

CAS:446-35-5 | 2,4-Difluoronitrobenzene ,Description

2,4-Difluoronitrobenzene is an organic compound with the chemical formula C6H3F2NO2. It is a yellow solid that is soluble in organic solvents and is used in the synthesis of pharmaceuticals, polymers, and other organic compounds. It is also used as an intermediate in the production of dyes, perfumes, and other chemicals. Its structure is characterized by a nitro group attached to the 2 and 4 positions of a benzene ring.
 

Scientific Research Applications

Chemical Reactions and Structures

• 2,4-Difluoronitrobenzene reacts with amines like aniline and ammonia, forming products with unique crystalline forms. These include a hydrogen-bonded hexamer or paddle-wheel motif, which shows one-dimensional channels and a dense framework in its pure form (Plater & Harrison, 2015).

Thermodynamic Properties

• The thermodynamic study of 2,4-Difluoronitrobenzene (2,4-DFNB) involves determining standard molar enthalpies of formation in various phases. This research is crucial for understanding its combustion and vaporization behaviors, which are relevant in industrial applications (Ribeiro da Silva et al., 2010).

Synthesis Optimization

• 2,4-Difluoro benzoic acid, a derivative of 2,4-Difluoronitrobenzene, was synthesized with a focus on optimizing reaction conditions. This process demonstrates how modifications in synthesis can significantly increase yield, emphasizing the compound's versatility in chemical synthesis (Luan Fang, 2004).

Spectroscopic and Molecular Properties

• Studies involving microwave spectroscopy and quantum chemical calculations have been used to investigate the internal rotation potential and molecular structure of 2,4-Difluoronitrobenzene. This research is crucial for understanding its molecular behavior and potential applications in materials science (Larsen & Nielsen, 2014).

Application in Organometallic Chemistry

• Partially fluorinated benzenes, including 2,4-Difluoronitrobenzene, are recognized for their utility in organometallic chemistry and transition-metal-based catalysis. These compounds serve as solvents or ligands due to their modified electron density and chemical inertness, highlighting their role in facilitating various chemical reactions (Pike et al., 2017).

Biodegradation Studies

• The biodegradation of difluorobenzenes, including 2,4-Difluoronitrobenzene, has been studied in microbial strains like Labrys portucalensis. This research is significant for understanding environmental impacts and potential applications in waste management or bioremediation (Moreira et al., 2009).

Photoluminescence and Fluorination Studies

• 2,4-Difluoronitrobenzene has been studied for its photoluminescence and fluorination properties. These studies are crucial in developing new materials with specific optical and chemical properties, useful in various technological applications (Jiang et al., 2006).

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