450-88-4 | 2-Bromo-5-fluoroanisole

CAS:450-88-4 | 2-Bromo-5-fluoroanisole,Description

Synthesis Analysis

The synthesis of halogenated anisoles like 2-Bromo-5-fluoroanisole can be inferred from the methodologies described in the papers. For instance, the continuous, homogeneous synthesis of 4-bromo-3-methylanisole in a microreaction system suggests that a similar approach could be applied to synthesize 2-Bromo-5-fluoroanisole with high selectivity and efficiency. The use of a modular microreaction system could potentially offer precise control over the reaction conditions, minimizing byproducts and improving the yield of the desired product.

Molecular Structure Analysis

While the molecular structure of 2-Bromo-5-fluoroanisole is not explicitly analyzed in the papers, the presence of bromo and fluoro substituents on an aromatic ring typically influences the electronic distribution and reactivity of the molecule. The electron-withdrawing effects of the fluorine atom and the relatively bulky bromine atom can affect the molecule's reactivity and interaction with other chemical species.

Chemical Reactions Analysis

The papers provide examples of chemical reactions involving bromo- and fluoro-substituted aromatic compounds. For example, the visible light-promoted fluoroalkylation of alkenes and alkynes using 2-bromophenol as a catalyst indicates that bromo-substituted phenols can participate in electron donor-acceptor (EDA) complex formation and subsequent reactions. This suggests that 2-Bromo-5-fluoroanisole could also engage in similar EDA complex-mediated reactions under appropriate conditions.

Physical and Chemical Properties Analysis

The physical and chemical properties of 2-Bromo-5-fluoroanisole can be partially deduced from the properties of related compounds discussed in the papers. The chemoselective amination of 5-bromo-2-chloro-3-fluoropyridine demonstrates the influence of halogen substituents on the reactivity of aromatic compounds, which is likely to be relevant to 2-Bromo-5-fluoroanisole as well. The selective reactivity observed in these compounds suggests that 2-Bromo-5-fluoroanisole may exhibit similar selectivity in its reactions, influenced by the positions of the bromo and fluoro substituents on the anisole ring.

Scientific Research Applications

“2-Bromo-5-fluoroanisole” is a type of methoxybenzene and is often used in the synthesis of other chemicals. Here are some potential applications based on its chemical properties:

• Organic Synthesis

  • “2-Bromo-5-fluoroanisole” can be used as a building block in organic synthesis. It can react with other compounds to form new substances, which can be used in various fields such as pharmaceuticals, agrochemicals, and materials science.

• Pharmaceutical Research

  • Given its chemical structure, “2-Bromo-5-fluoroanisole” could potentially be used in the development of new drugs. For example, it could be used to synthesize new compounds with potential therapeutic effects.

“2-Bromo-5-fluoroanisole” is a type of methoxybenzene and is often used in the synthesis of other chemicals. Here are some potential applications based on its chemical properties:

• Organic Synthesis

  • “2-Bromo-5-fluoroanisole” can be used as a building block in organic synthesis. It can react with other compounds to form new substances, which can be used in various fields such as pharmaceuticals, agrochemicals, and materials science.

• Pharmaceutical Research

  • Given its chemical structure, “2-Bromo-5-fluoroanisole” could potentially be used in the development of new drugs. For example, it could be used to synthesize new compounds with potential therapeutic effects.

Safety And Hazards

2-Bromo-5-fluoroanisole is classified as a skin irritant, serious eye irritant, and may cause respiratory irritation. It’s recommended to avoid breathing its dust, fume, gas, mist, vapors, or spray, and to use it only outdoors or in a well-ventilated area.

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