460-37-7 | 1,1,1-Trifluoro-3-iodopropane

CAS:460-37-7 | 1,1,1-Trifluoro-3-iodopropane ,Description

1,1,1-Trifluoro-3-iodopropane (TFIP) is a highly reactive halogenated organic compound that has been used in a variety of scientific research applications. TFIP is a colorless gas with a pungent odor and a boiling point of -32.2 °C. It is a member of the halogenated alkanes family and is commonly used as a reagent in organic synthesis. TFIP is a versatile reagent that has been used in a variety of laboratory experiments, including the synthesis of polymers, the production of pharmaceuticals, and the study of biochemical and physiological effects.
 

Scientific Research Applications

Chemical Reactions and Mechanisms

• β-Hydride Elimination Reactions: 1,1,1-Trifluoro-3-iodopropane is utilized in the study of β-hydride elimination reactions. The kinetics of this reaction in trifluoropropyl groups on the Cu(111) surface have been examined, providing insights into the behavior of these groups under specific conditions (Forbes & Gellman, 1993).

Spectroscopic Analysis

• Ultra-Violet Spectra Studies: It has been used in the study of far-ultra-violet spectra, aiding in the understanding of the spectroscopic properties of fluoro-iodo-alkanes and related compounds (Boschi & Salahub, 1972).

Radical Reactions

• Free-Radical Additions: The compound has been investigated in the context of free-radical additions to unsaturated systems, demonstrating its reactivity and the formation of various adducts (Haszeldine, Keen, & Tipping, 1970).

Polymer Research

• Fluorocarbon Polymer Models: It plays a role in the synthesis of models for fluorocarbon polymers, particularly in telomerization reactions, highlighting its significance in polymer chemistry (Chambers, Hutchinson, Mobbs, & Musgrave, 1964).

Medicinal Chemistry

• Radiolabeling Applications: The compound is used in radiolabeling, specifically in the preparation of 18F-labeled amines, showcasing its application in medical imaging and diagnostics (Chesis & Welch, 1990).

Photoelectron Spectroscopy

• High-Resolution Photoelectron Spectra: Its use in high-resolution photoelectron spectroscopy provides valuable data for the study of iodine-containing molecules and their electronic structures (Boschi & Salahub, 1974).

Synthetic Chemistry

• Synthesis of Aminoester: Demonstrated in the practical synthesis of trifluoromethyl-containing aminoester, where its reactivity and utility in organic synthesis are highlighted (Alimardanov, Schmid, Afragola, & Khafizova, 2008).

Atmospheric Chemistry

• Atmospheric Lifetimes Estimation: The compound has been studied to estimate its atmospheric lifetime, particularly in relation to sunlight photolysis and reactions with NO3, contributing to our understanding of atmospheric chemistry (Nakano, Shibata, & Watanabe, 2017).

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