58244-27-2 | Tris(2,2,2-trifluoroethyl)orthoformate

CAS:58244-27-2 | Tris(2,2,2-trifluoroethyl)orthoformate ,Description

Tris(2,2,2-trifluoroethyl)orthoformate, also known as Trifluoroacetic Acid Anhydride (TFAA), is a colorless and odorless liquid that is used in a variety of laboratory experiments and industrial applications. It is an organic compound with the formula C3H3F3O3 and is a derivative of trifluoroacetic acid. TFAA is a versatile reagent with a wide range of uses in organic synthesis, and is also used in the synthesis of pharmaceuticals and other materials.
The fluorinated lithium battery additive acts to form a film and increase the flash point.

Scientific Research Applications

1. Application in Lithium-Ion Batteries

Tris(2,2,2-trifluoroethyl)orthoformate has shown potential in the realm of lithium-ion batteries. A study demonstrated its effectiveness as an additive during the initial activation and cycling of Li-rich-NMC xLi2MnO3–(1−x)LiMO2 cathode in EC/DMC + 1 M LiPF6 electrolyte. This inclusion improved conductivity and viscosity of the electrolyte, indicating promising applications for high-performance batteries (Pires et al., 2015).

2. Role in Organic Synthesis

In organic chemistry, Tris(2,2,2-trifluoroethyl)orthoformate serves as a reagent for the formation of various imines by condensation of amides or amines with carbonyl compounds. This method is noted for its simplicity and efficiency, providing a versatile tool for synthesizing a wide range of organic compounds (Reeves et al., 2015).

3. Analytical Chemistry Applications

In the field of analytical chemistry, Tris(2,2,2-trifluoroethyl)orthoformate has been utilized for amino acid analysis. Specifically, it was used to derive amino acids into N(O)-alkoxycarbonyl alkyl esters, facilitating the rapid separation of enantiomeric isomers by capillary gas chromatography. This method highlights its utility in precise analytical procedures, contributing significantly to the field of chiral analysis (Abe et al., 1996).

4. Electrolyte Development for Safety in Lithium-Ion Batteries

Tris(2,2,2-trifluoroethyl)orthoformate's role extends to the development of safer electrolytes for lithium-ion batteries. It was part of a novel electrolyte formulation containing lithium difluoro(oxalato)borate, propylene carbonate, and fluoroethylene carbonate additive, enhancing safety and performance aspects of lithium-ion batteries. This application demonstrates its potential in enhancing battery technology, particularly in terms of safety and efficiency (Gu et al., 2020).

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