637031-93-7 | 3,3-Difluorocyclobutanamine hydrochloride

CAS:637031-93-7 | 3,3-Difluorocyclobutanamine hydrochloride ,Description

3,3-Difluorocyclobutanamine hydrochloride (3,3-DFCB-HCl) is a cyclic amine compound that has been studied for its potential applications in scientific research. It is a colorless and odorless solid with a melting point of 162-165 °C. The chemical structure of 3,3-DFCB-HCl consists of a cyclobutane ring with two fluorine atoms, and a hydrochloride group. This compound has been used as a starting material for various chemical syntheses, and has been studied for its potential in biochemical and physiological research. In 
 

Scientific Research Applications

Membrane Interaction Studies

Research has shown that fluorinated compounds like 1-chloro-1,2,2-trifluorocyclobutane exhibit significant anesthetic properties. These compounds interact differently with biomembranes, influencing their distribution in various membrane regions. This differential distribution is pivotal in understanding the mechanism of anesthetics versus nonanesthetics. Such studies are essential in pharmacology and biochemistry for drug development and understanding drug action mechanisms (Tang, Yan, & Xu, 1997).

Synthesis and Characterization of Derivatives

Significant work has been done in synthesizing and characterizing difluorocyclobutane derivatives. For example, efficient approaches to synthesize 2-substituted difluorocyclobutane building blocks were developed. Such research is fundamental in organic chemistry, providing building blocks for further chemical synthesis and drug development (Chernykh et al., 2019).

Multigram Synthesis of Building Blocks

The multigram synthesis of 3,3-difluorocyclobutyl-substituted building blocks, including carboxylic acid, amines, and alcohols, has been described. This synthesis is crucial for the large-scale production of these compounds, which can be used in various research and industrial applications (Ryabukhin et al., 2018).

Organic Geochemistry Applications

In geochemistry, techniques like HF-BF3 maceration are used for concentrating and isolating dispersed organic matter. This process involves reactions with fluorinated compounds, highlighting their utility in geochemical analysis and environmental studies (Robl & Davis, 1993) .

Facilitating Chemical Reactions

Fluorinated cyclobutanes are used to facilitate various chemical reactions. For instance, they have been employed in the synthesis of protected amino compounds, which are important intermediates in medicinal chemistry. Such reactions are vital for the development of new pharmaceuticals and therapeutic agents (Mohammad et al., 2020).

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