65864-64-4 | (Difluoromethyl)trimethylsilane

CAS:65864-64-4 | (Difluoromethyl)trimethylsilane ,Description

(Difluoromethyl)trimethylsilane, also known as (CF3)2SiH, is an organosilicon compound that is used in a variety of scientific and industrial applications. It is a colorless and volatile liquid with a boiling point of 39.5 °C and a molecular weight of 118.15 g/mol. It is a highly reactive compound and is used as a reagent in the synthesis of organosilicon compounds, as a catalyst in organic reactions, and as a precursor for various other organosilicon compounds.
 

Scientific Research Applications

• Replacement Reactions: It performs various replacement reactions, like halogen substitution and dehydrohalogenation (González, Foti, & Elsheimer, 2003) .
• Nucleophilic Difluoromethylation: This compound is used for the nucleophilic difluoromethylation of ketones and nitro alkenes (Trifonov et al., 2016).
• Synthesis of Fluoroorganic Compounds: It's employed in the syntheses of fluoroorganic compounds, aiding in introducing polyfluorinated groups into various compounds (Furin & Bardin, 1991).
• Synthesis of Perfluorinated Diketones: Useful in the synthesis of perfluorinated diketones, which have applications in scientific research (Anderson, Pennington, & Desmarteau, 1993).
• Preparation of Perfluoroalkyl and Perfluoroaryl Compounds: It facilitates the efficient preparation of known and new perfluoroalkyl and perfluoroaryl compounds (Patel & Kirchmeier, 1992).
• Synthesis of Trifluoromethyl Sulfides: It's used for synthesizing bio-active trifluoromethyl sulfides and in nucleophilic trifluoromethylation of non-enolizable carbonyl compounds or disulfides (Langlois & Billard, 2003).
• Synthesis of 1,1-Difluoroalkenes: This compound is used in the synthesis of 1,1-difluoroalkenes, which are precursors for organic synthesis and enzyme inhibitors (Wang, Li, Ni, & Hu, 2014).
• Oxidative Gold Oxyarylation Reactions: It plays a role in oxidative gold oxyarylation reactions, offering competent coupling partners and reducing homocoupling byproducts (Brenzovich, Brazeau, & Toste, 2010).
• Pharmaceuticals, Materials, and Agrochemicals: It's significant in nucleophilic trifluoromethylation reactions, which are important in the development of pharmaceuticals, materials, and agrochemicals (Krishnamoorthy & Prakash, 2017).
• Preparation of Tri- and Difluoromethylated Amines: Used to prepare amines from aldimines for research applications (Prakash, Mogi, & Olah, 2006).
• Novel Perfluoroalkyl-Substituted Compounds: Aids in preparing novel perfluoroalkyl-substituted compounds in high yields (Krishnamurti, Bellew, & Prakash, 1991).

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