67815-56-9 | 2,3,6-TRIFLUOROANILINE

CAS:67815-56-9 | 2,3,6-TRIFLUOROANILINE,Description

2,3,6-Trifluoroaniline is a chemical compound with the linear formula F3C6H2NH2. It is used in the preparation of sirt6 small-molecule allosteric activators.

Molecular Structure Analysis

The molecular structure of 2,3,6-Trifluoroaniline consists of a six-membered carbon ring (benzene) with three fluorine atoms and one amine group (NH2) attached. The molecular weight is 147.10.

Physical And Chemical Properties Analysis

2,3,6-Trifluoroaniline is a solid at room temperature with a density of 1.39 g/mL at 25 °C. It has a refractive index of 1.487.

Scientific Research Applications

Application in Environmental Science

• Specific Scientific Field: Environmental Science.
• Summary of the Application: Trifluoroaniline compounds, such as 2,3,4-Trifluoroaniline, have been studied for their effects on the environment, particularly due to contamination with fluoroaromatics (FAs). These compounds are becoming a serious environmental problem worldwide.
• Methods of Application or Experimental Procedures: The study focused on the effects of three seeding sources on treatment performances of 2,3,4-Trifluoroaniline during start-up and shock, as well as the acclimated strategy. After 246–323 days of acclimation in a stepwise feeding according to the inhibition degree, three sequencing batch reactors (SBRs) successfully achieved efficient removal.
• Results or Outcomes: The sludge obtained from the fluorizated hydrocarbon wastewater treatment plant (FHS) without prior exposure to fluoroaniline was determined to be optimal, based on the observed shortest start-up time of 246 days, the highest defluorination rate of 70.00–80.00%, the fastest recovery time of 7 days after shock, and the highest microbial diversity with nine dominant bacterial groups.

Application in Chemical Synthesis

• Specific Scientific Field: Chemical Synthesis.
• Summary of the Application: 2,4,6-Trifluoroaniline has been used in the synthesis of various compounds.
• Results or Outcomes: The compounds synthesized using 2,4,6-Trifluoroaniline include 3-nitro-2,4,6-trifluoroacetanilide, a series of N′-phenyl-N-(1-phenyl cyclopentyl)-methyl ureas, and 4-substituted 2,6-difluoro N-aryl pyridinones.

Safety And Hazards

2,3,6-Trifluoroaniline is considered hazardous. It’s recommended to avoid all personal contact, including inhalation. Use protective clothing when there’s a risk of overexposure and use only in a well-ventilated area.

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