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705-09-9 | 2-Difluoromethyl-1H-benzoimidazole

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Purchase CAS:705-09-9 | 2-Difluoromethyl-1H-benzoimidazole,view related peer-reviewed papers,technical documents,similar products,MSDS & more.2-(Difluoromethyl)-1H-benzimidazole is a chemical compound. However, there is limited information available about this specific compound12....
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CAS:705-09-9 | 2-Difluoromethyl-1H-benzoimidazole,Description

2-(Difluoromethyl)-1H-benzimidazole is a chemical compound. However, there is limited information available about this specific compound12.


 

 

Synthesis Analysis

The synthesis of difluoromethyl compounds has been a topic of interest in recent years34. However, the specific synthesis process for 2-(Difluoromethyl)-1H-benzimidazole is not readily available in the sources I found.
 

 

Molecular Structure Analysis

The molecular structure of a compound can provide insights into its properties and potential applications567. However, the specific molecular structure analysis for 2-(Difluoromethyl)-1H-benzimidazole is not detailed in the sources I found.
 

 

Chemical Reactions Analysis

Chemical reactions involving difluoromethyl compounds have been studied89. However, specific chemical reactions involving 2-(Difluoromethyl)-1H-benzimidazole are not detailed in the sources I found.
 

 

Physical And Chemical Properties Analysis

The physical and chemical properties of a compound can provide insights into its potential applications1213. However, the specific physical and chemical properties of 2-(Difluoromethyl)-1H-benzimidazole are not detailed in the sources I found.
 

 

Scientific Research Applications

 

  • Scientific Field : Organic Chemistry 
  • Summary of the Application : Difluoromethylation is a process that involves the formation of X–CF2H bonds, where X can be C (sp), C (sp2), C (sp3), O, N, or S. This process is of prime importance due to its applicability in functionalizing diverse fluorine-containing heterocycles, which are the core moieties of various biologically and pharmacologically active ingredients.
  • Methods of Application or Experimental Procedures : The difluoromethylation process has benefited from the invention of multiple difluoromethylation reagents. The last decade has witnessed an upsurge of metal-based methods that can transfer CF2H to C (sp2) sites both in stoichiometric and catalytic mode. Difluoromethylation of C (sp2)–H bond has also been accomplished through Minisci-type radical chemistry, a strategy best applied to heteroaromatics.
  • Results or Outcomes : These advances have streamlined access to molecules of pharmaceutical relevance, and generated interest for process chemistry. The construction of difluoromethyl substituted scaffolds has been a highly intriguing research topic, and substantial progress has been made in the past decades.
  • Scientific Field : Organic Chemistry 
  • Summary of the Application : Difluoromethylation is a process that involves the formation of X–CF2H bonds, where X can be C (sp), C (sp2), C (sp3), O, N, or S. This process is of prime importance due to its applicability in functionalizing diverse fluorine-containing heterocycles, which are the core moieties of various biologically and pharmacologically active ingredients.
  • Methods of Application or Experimental Procedures : The difluoromethylation process has benefited from the invention of multiple difluoromethylation reagents. The last decade has witnessed an upsurge of metal-based methods that can transfer CF2H to C (sp2) sites both in stoichiometric and catalytic mode. Difluoromethylation of C (sp2)–H bond has also been accomplished through Minisci-type radical chemistry, a strategy best applied to heteroaromatics.
  • Results or Outcomes : These advances have streamlined access to molecules of pharmaceutical relevance, and generated interest for process chemistry. The construction of difluoromethyl substituted scaffolds has been a highly intriguing research topic, and substantial progress has been made in the past decades.
  • Scientific Field : Organic Chemistry 
  • Summary of the Application : Difluoromethylation is a process that involves the formation of X–CF2H bonds, where X can be C (sp), C (sp2), C (sp3), O, N, or S. This process is of prime importance due to its applicability in functionalizing diverse fluorine-containing heterocycles, which are the core moieties of various biologically and pharmacologically active ingredients.
  • Methods of Application or Experimental Procedures : The difluoromethylation process has benefited from the invention of multiple difluoromethylation reagents. The last decade has witnessed an upsurge of metal-based methods that can transfer CF2H to C (sp2) sites both in stoichiometric and catalytic mode. Difluoromethylation of C (sp2)–H bond has also been accomplished through Minisci-type radical chemistry, a strategy best applied to heteroaromatics.
  • Results or Outcomes : These advances have streamlined access to molecules of pharmaceutical relevance, and generated interest for process chemistry. The construction of difluoromethyl substituted scaffolds has been a highly intriguing research topic, and substantial progress has been made in the past decades.

Safety And Hazards

Understanding the safety and hazards of a compound is crucial for its handling and use1415. However, the specific safety and hazards associated with 2-(Difluoromethyl)-1H-benzimidazole are not detailed in the sources I found.


 

 

Future Directions

Research into difluoromethyl compounds continues to be a topic of interest, with potential applications in various fields1617. However, the specific future directions for research into 2-(Difluoromethyl)-1H-benzimidazole are not detailed in the sources I found.


 

Please note that while I strive to provide accurate and up-to-date information, the details provided should be verified with a reliable source or expert in the field. The information provided is based on the sources I found and may not be comprehensive or entirely accurate.


 

More Information

Product Name:2-Difluoromethyl-1H-benzoimidazole
Synonyms:1H-benzo[d]imidazole, 2-(difluoromethyl)-;2-(Difluoromethyl);1H-Benzimidazole,2-(difluoromethyl)-(9CI);2-Difluoromethyl-1H-benzoimidazole;2-(difluoromethyl)-1H-benzimidazole(SALTDATA: FREE);2-(Difluoromethyl)-1H-benzimidazole;2-(difluoroMethyl)-1H-1,3-benzodiazole;2-Difluoromethylbenzimidazole
CAS:705-09-9
MF:C8H6F2N2
MW:168.14
EINECS: 
Product Categories:BENZIMIDAZOLE
Mol File:705-09-9.mol
 
2-Difluoromethyl-1H-benzoimidazole Chemical Properties
Melting point 155.0 to 159.0 °C
Boiling point 57-62 °C(Press: 5 Torr)
density 1.366±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility soluble in Methanol
form powder to crystal
pka10.43±0.10(Predicted)
color White to Light yellow to Light orange
λmax276nm(EtOH)(lit.)

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MS

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1HNMR

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CNMR

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IR1

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IR2

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Raman


 

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