71027-02-6 | 4,4,4-Trifluorocrotonic acid

CAS:71027-02-6 | 4,4,4-Trifluorocrotonic acid ,Description

4,4,4-Trifluorocrotonic acid (TFCA) is a versatile, organofluorine compound with a wide range of applications. It is an important intermediate in the synthesis of a variety of organic compounds, including pharmaceuticals, agrochemicals, and dyes. The compound is also widely used in the synthesis of fluorinated materials such as polymers, surfactants, and fluorinated carbonates. TFCA has been extensively studied due to its unique structure and reactivity. 
 

Scientific Research Applications

Catalysis and Organic Synthesis

• Formal Reductive Annulation: A study by Kondoh & Terada (2020) explored the use of 4,4,4-trifluorocrotonate in the formal reductive [3+2] annulation with α-iminoketones under Brønsted base catalysis. This process generates β-trifluoromethyl-substituted γ-lactams, demonstrating the compound's utility in synthesizing complex organic structures (Kondoh & Terada, 2020) .

Chemical Properties and Interactions

• Conformational Landscape in Fluorine-Containing Alcohols: Lu et al. (2020) investigated 4,4,4-trifluoro-1-butanol, a compound structurally related to 4,4,4-trifluorocrotonic acid. Their study focused on understanding the conformational flexibility and relaxation pathways of this compound, contributing to the broader understanding of fluorine-containing alcohols in chemical reactions (Lu et al., 2020).

Environmental and Material Science Applications

• Electrochemical Applications: Research by Kim et al. (2018) on ethyl 4,4,4-trifluorobutyrate, a derivative of 4,4,4-trifluorocrotonic acid, revealed its application in enhancing the performance of Ni-rich cathodes and stable graphite anodes in batteries. This study highlights the potential of fluorinated compounds in improving energy storage technologies (Kim et al., 2018).

Photodissociation and Environmental Impact

• Photodissociation and Environmental Impact: Sengupta et al. (2018) studied the photodissociation of trifluoroacetic acid at 193 nm, a process relevant to the environmental impact of fluorinated compounds. The study provides insights into the formation of OH radicals and stable products, contributing to the understanding of the atmospheric behavior of similar compounds (Sengupta et al., 2018).

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