72505-21-6 | 4-(Trifluoromethyl)thiobenzamide

CAS:72505-21-6 | 4-(Trifluoromethyl)thiobenzamide,Description

4-(Trifluoromethyl)thiobenzamide is a chemical compound with the molecular formula C8H6F3NS and a molecular weight of 205.20. It is used in laboratory settings.

Molecular Structure Analysis

The molecular structure of 4-(Trifluoromethyl)thiobenzamide consists of a benzene ring substituted with a trifluoromethyl group and a thiobenzamide group.

Physical And Chemical Properties Analysis

4-(Trifluoromethyl)thiobenzamide is a solid at 20 degrees Celsius.

Scientific Research Applications

Corrosion Inhibition

4-(Trifluoromethyl)thiobenzamide and related thiobenzamides are studied for their role in corrosion inhibition. These compounds, particularly thiobenzamide, have demonstrated significant efficiency in protecting mild steel from corrosion in acidic environments. Their effectiveness is attributed to the thiocarbonyl group and varies with different substituents on the thiocarbonyl group. Electrochemical impedance spectroscopy and polarization resistance measurement techniques are used to evaluate their performance, with quantum chemical calculations providing insight into the molecular structures and their relation to corrosion inhibition (Özcan & Dehri, 2004) .

Photochromic Properties

Thiobenzamide derivatives have been explored for their photochromic properties. These studies involve synthesizing compounds like 4-hetaryl-5,6-(2,5-dimethyl-3-thienyl)-2-phenyl-4H-thiazines through reactions with thiobenzamide and evaluating their photochromic behavior. This area of research delves into the potential applications of these compounds in light-responsive materials (Belen’kii et al., 2005) .

Synthesis of Benzothiazoles

A significant application of thiobenzamide derivatives is in the synthesis of benzothiazoles through intramolecular cyclization. This process, facilitated by agents like phenyliodine(III) bis(trifluoroacetate), converts thiobenzamides into benzothiazoles. This method offers a general and efficient pathway for creating these compounds, which are important in various chemical and pharmaceutical contexts (Downer-Riley & Jackson, 2008).

Trifluoromethylating Agents

Thiobenzamide derivatives are also significant in the development of trifluoromethylating agents. These agents are crucial for introducing trifluoromethyl groups into various organic compounds, enhancing their chemical properties and utility in diverse fields like pharmaceuticals and materials science. Research in this area focuses on creating efficient and versatile trifluoromethylating agents (Umemoto & Ishihara, 1993).

Luminescence in Coordination Compounds

4-(Trifluoromethyl)thiobenzamide analogs have been synthesized for use in coordination compounds that exhibit luminescence. These compounds, when complexed with lanthanide metal ions like europium and terbium, show distinct luminescent properties under UV light, suggesting potential applications in materials science and sensor technologies (Walton & Bettencourt-Dias, 2014).

Safety And Hazards

4-(Trifluoromethyl)thiobenzamide is considered hazardous. It is toxic if swallowed, causes skin irritation, and can cause serious eye irritation. It should be handled with care, using protective gloves, eye protection, and face protection.

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