762-51-6 | 1-Fluoro-2-iodoethane

CAS:762-51-6 | 1-Fluoro-2-iodoethane ,Description

1-Fluoro-2-iodoethane, also known as 1-iodo-2-fluoroethane, is a halogenated hydrocarbon and a colorless, volatile liquid. It is an alkylating agent, meaning it forms covalent bonds with nucleophiles, and is used in a variety of applications, including medical and industrial research. It is highly reactive and has a low boiling point, making it a useful compound for a variety of purposes.
 

Scientific Research Applications

Vibrational Analysis and Rotational Isomers

1-Fluoro-2-iodoethane has been studied for its vibrational characteristics in various states (solid, liquid, and vapor) and rotational isomers. Research conducted by Bermani and Jonathan (1968) in the Journal of Chemical Physics revealed that in 1-fluoro-2-iodoethane, the gauche isomer is more stable in the liquid state, while the trans form is preferred in vapor. These findings provide insights into the molecular behavior and stability of different isomers under various conditions (Bermani & Jonathan, 1968) .

Theoretical Study of Rotational Isomerism

Serboli and Minasso (1971) conducted a theoretical study and infrared analysis of compounds related to 1-fluoro-2-iodoethane, which showed the presence of different isomeric forms. This study enhances the understanding of the molecular dynamics and potential energy of these compounds, providing valuable information for chemical synthesis and analysis (Serboli & Minasso, 1971).

Fluoroalkylation Reagents

Dai et al. (2016) in Organic & Biomolecular Chemistry developed a heterobifunctional fluoroalkylation reagent, 1-azido-2-chloro-1,1,2-trifluoro-2-iodoethane (ACTI), demonstrating its versatility in preparing fluorinated organic compounds. This research presents 1-fluoro-2-iodoethane derivatives as potential tools in organic synthesis, particularly in introducing fluorine atoms into organic molecules (Dai et al., 2016).

Gas Phase Study of Conformers

The gas phase behavior of 1-fluoro-2-iodoethane and similar molecules was analyzed by Ramasami (2006), focusing on the gauche and trans conformers. The absence of a gauche effect, indicating a preference for the trans conformer, was noted. This study is significant for understanding the molecular structure and stability in the gas phase, which is crucial for various chemical processes and applications (Ramasami, 2006).

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