79667-91-7 | 2,2-Difluoroethylamine hydrochloride

CAS:79667-91-7 | 2,2-Difluoroethylamine hydrochloride ,Description

2,2-Difluoroethylamine hydrochloride, also known as 2,2-difluoroethanamine hydrochloride, is an organic compound that is used in the synthesis of various pharmaceuticals and other compounds. It is a white, crystalline solid with a melting point of around 100 °C. It is highly soluble in water, alcohol, and other solvents. The compound is commonly used in the synthesis of pharmaceutical drugs, as well as in the manufacture of agrochemicals, dyes, and other industrial compounds.
 

Scientific Research Applications

Perovskite Solar Cells Efficiency Improvement

2,2-Difluoroethylamine hydrochloride is used in perovskite solar cells for defect passivation. The integration of fluoroethylamine into the perovskite film helps suppress nonradiative recombination, improve carrier lifetime, and enhance film hydrophobicity, which contributes to higher efficiency and superior stability of these solar cells (Su et al., 2021).

Synthesis Methodology

The synthesis of 2,2-difluoroethylamine via amination of 1-halo-2,2-difluoroethane is another important application. This process involves experimental and theoretical studies to understand the complexity and mechanisms of the reaction. It's significant for producing 2,2-difluoroethylamine more efficiently and understanding its chemical properties (Han et al., 2020).

Novel Fluorinated Compounds for Measuring Tumor-Hypoxia

2,2-Difluoroethylamine hydrochloride derivatives have been developed as probes for measuring tumor-hypoxia using 19F-magnetic resonance spectroscopy. These fluorinated hypoxia-targeted compounds bind to hypoxic cells in tumors, allowing non-invasive detection and measurement of tumor hypoxia (Papadopoulou et al., 2006).

Conformational Analysis

Research on the conformational analysis of 2,2-difluoroethylamine hydrochloride has been conducted to understand its structural properties. This includes studying the gauche effect in fluorinated alkylammonium salts and the implications of adding fluorine atoms to the compound (Silla et al., 2014).

Determination of Methamphetamine Hydrochloride

2,2-Difluoroethylamine hydrochloride has been used in the analytical determination of Methamphetamine Hydrochloride, showcasing its potential in forensic and pharmaceutical analysis (He et al., 2011).

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