83282-91-1 | 4-Methoxymethyl-2,3,5,6-tetrafluorobenzyl alcohol

CAS:83282-91-1 | 4-Methoxymethyl-2,3,5,6-tetrafluorobenzyl alcohol ,Description

4-Methoxymethyl-2,3,5,6-tetrafluorobenzyl alcohol (4-MTFB) is a synthetic compound that has been used in research laboratories for a variety of purposes. It is a colorless, water-soluble alcohol that is relatively stable and has a low toxicity. 4-MTFB has been used in the synthesis of various compounds, including pharmaceuticals, agrochemicals, and intermediates. It has also been used in various biochemical and physiological experiments, such as enzyme inhibition and receptor binding assays. 
 

Scientific Research Applications

Biomarker for Pyrethroid Exposure

Monitoring Metofluthrin Exposure4-Methoxymethyl-2,3,5,6-tetrafluorobenzyl alcohol has been identified as an optimal urinary biomarker for monitoring exposure to metofluthrin, a fluorine-containing pyrethroid widely used in mosquito repellents. This compound's presence in urine is proportional to the absorption amounts of metofluthrin, making it a reliable indicator for assessing exposure levels in the general population (Yoshida, 2015).

Analytical Chemistry Applications

Analytical Method DevelopmentAn analytical method utilizing gas chromatography/mass spectrometry has been developed for measuring major urinary metabolites of fluorine-containing pyrethroids (including metofluthrin, profluthrin, and transfluthrin). This method allows for the extraction and quantification of 4-Methoxymethyl-2,3,5,6-tetrafluorobenzyl alcohol among other metabolites, providing a precise and accurate tool for pyrethroid metabolite analysis (Yoshida, 2013).

Electrochemical Applications

Electrochemical ReductionResearch has explored the electrochemical reduction of fluorinated aromatic carboxylic acids, including the selective reduction of pentafluorobenzoic acid to compounds like 2,3,5,6-tetrafluorobenzyl alcohol. These studies contribute to understanding the electrochemical properties and potential synthetic pathways involving fluorinated compounds, highlighting the versatile applications of 4-Methoxymethyl-2,3,5,6-tetrafluorobenzyl alcohol and related substances (Drakesmith, 1972).

Synthesis and Catalysis

Photocatalytic OxidationThe photocatalytic oxidation of benzyl alcohol and its derivatives into corresponding aldehydes using titanium dioxide under visible light irradiation is an area of research demonstrating the potential application of similar compounds in synthetic organic chemistry. This process showcases the efficiency of photocatalysis in transforming compounds with structures related to 4-Methoxymethyl-2,3,5,6-tetrafluorobenzyl alcohol (Higashimoto et al., 2009).

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