843644-23-5 | 6,8-Difluoro-2-tetralone

CAS:843644-23-5 | 6,8-Difluoro-2-tetralone,Description

6,8-Difluoro-2-tetralone is a chemical compound with the formula C10H8F2O¹. It is a solid substance6,8-Difluoro-2-tetralone is a chemical compound with the formula C10H8F2O1" h="ID=SERP,5015.1">².

Synthesis Analysis

Unfortunately, I couldn’t find specific information on the synthesis of 6,8-Difluoro-2-tetralone. However, it is commercially available from several suppliers².
 

Molecular Structure Analysis

The molecular structure of 6,8-Difluoro-2-tetralone is represented by the formula C10H8F2O¹. The InChI code for this compound is 1S/C10H8F2O/c11-7-3-6-1-2-8(13)5-9(6)10(12)4-7/h3-4H,1-2,5H2The molecular structure of 6,8-Difluoro-2-tetralone is represented by the formula C10H8F2O1" h="ID=SERP,5015.1">¹.
 

Chemical Reactions Analysis

I’m sorry, but I couldn’t find specific information on the chemical reactions involving 6,8-Difluoro-2-tetralone.
 

Physical And Chemical Properties Analysis

6,8-Difluoro-2-tetralone is a solid substance². It has a molecular weight of 182.176,8-Difluoro-2-tetralone is a solid substance2" h="ID=SERP,5015.1">². The boiling point is predicted to be 260.6±40.0 °C².
 

Scientific Research Applications

Synthesis Techniques and Modifications

6,8-Difluoro-2-tetralone, while not directly mentioned, is closely related to other tetralones in terms of chemical structure and potential applications. Various synthesis techniques and modifications of tetralone compounds have been explored:

• Isopropylation of Tetralones : The isopropylation process of methoxy-tetralones, including 5-methoxy-1-tetralone and 7-methoxy-1-tetralone, has been studied using isopropanol and polyphosphoric acid. This method could potentially be applied to 6,8-difluoro-2-tetralone for modifying its properties (Cabrera et al., 2015).
• Alternative Synthesis Routes : Different synthesis approaches for tetralones have been reported. One method involves starting from 2-bromophenylacetic acid, using a Friedel-Crafts acylation/cyclization, and subsequent steps for producing 8-methoxy-2-tetralone (Lee, Frescas & Nichols, 1995).
• Catalytic Transformations : The transformation of methoxy tetralones using boron trifluoride etherate and acetic anhydride has been explored. This method might be relevant for catalytic transformations of 6,8-difluoro-2-tetralone (Banerjee et al., 2004).

Potential Applications in Biomedical Fields

Tetralone derivatives, similar to 6,8-difluoro-2-tetralone, have been investigated for various biomedical applications:

• Dopaminergic Compounds Synthesis : Tetralones have been used in the synthesis of dopaminergic argonists, implying a potential use of 6,8-difluoro-2-tetralone in the preparation of neurological drugs (Horn et al., 1978).
• Biotransformation Studies : The biotransformation of bromo-tetralone to bromo-tetralol using yeast cells has been evaluated in an electrochemical bioreactor. This indicates the potential of 6,8-difluoro-2-tetralone in similar biotransformation processes (Shin, Jain, Chartrain & Zeikus, 2001).
• Electrochemical Studies : The electrochemical behavior of tetralone compounds in aprotic media has been investigated, suggesting potential applications of 6,8-difluoro-2-tetralone in electrochemical processes (Shekhawat, Sharma, Bhargava & Sharma, 2013).

These insights demonstrate the versatility of tetralone derivatives in chemical synthesis and potential biomedical applications, which could extend to 6,8-difluoro-2-t

Scientific Research Applications of 6,8-Difluoro-2-tetralone

Chemical Synthesis and Modification Techniques

• Isopropylation of Tetralone Derivatives : Research indicates successful isopropylation of various methoxy-tetralones using isopropanol and polyphosphoric acid. This technique could be relevant for modifying 6,8-Difluoro-2-tetralone to enhance its properties or for creating new derivatives (Cabrera et al., 2015).
• Friedel-Crafts Acylation/Cyclization : A method involving Friedel-Crafts acylation/cyclization has been used for preparing 8-Methoxy-2-tetralone, starting from 2-bromophenylacetic acid. Similar approaches might be applicable to 6,8-Difluoro-2-tetralone (Lee, Frescas & Nichols, 1995).
• Boron Trifluoride Etherate and Acetic Anhydride Transformation : Tetralone derivatives have been transformed using boron trifluoride etherate and acetic anhydride, suggesting potential methodologies for altering 6,8-Difluoro-2-tetralone (Banerjee et al., 2004).

Biomedical Applications

• Synthesis of Dopaminergic Compounds : Tetralones have been used for synthesizing dopaminergic argonists, indicating that 6,8-Difluoro-2-tetralone might have potential applications in the development of neurological drugs (Horn et al., 1978).
• Biotransformation Studies : The biotransformation of bromo-tetralone derivatives in an electrochemical bioreactor has been evaluated, suggesting that similar studies could be conducted with 6,8-Difluoro-2-tetralone (Shin, Jain, Chartrain & Zeikus, 2001).
• Electrochemical Behavior Analysis : The electrochemical behavior of tetralone derivatives has been studied, which may provide insights into the electrochemical properties of 6,8-Difluoro-2-tetralone (Shekhawat, Sharma, Bhargava & Sharma, 2013).

Safety And Hazards

The safety information available indicates that 6,8-Difluoro-2-tetralone may be harmful if swallowed, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation². Precautionary measures include washing hands and face thoroughly after handling, wearing protective gloves and eye protection, and avoiding breathing dust or fumesThe safety information available indicates that 6,8-Difluoro-2-tetralone may be harmful if swallowed, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation2" h="ID=SERP,5015.1">².

Future Directions

I couldn’t find specific information on the future directions of 6,8-Difluoro-2-tetralone research. However, given its unique properties, it could be a subject of interest in various fields of study.

Please note that while I strive to provide accurate and up-to-date information, it’s always a good idea to consult a professional or conduct further research for more detailed information.

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