844648-22-2 | 5,7-difluorochroman-4-one

CAS:844648-22-2 | 5,7-difluorochroman-4-one,Description

5,7-Difluorochroman-4-one is a chemical compound with the molecular formula C9H6F2O2. It is used as a reagent in the preparation of tetrazolinone compounds and as pest control agents.

Synthesis Analysis

The synthesis of 5,7-Difluorochroman-4-one involves taking it as a substrate and performing an asymmetric reduction reaction in the presence of ketoreductase, coenzyme, and a coenzyme circulating system.

Molecular Structure Analysis

The molecular structure of 5,7-Difluorochroman-4-one is characterized by a chroman ring (a benzene ring fused to a heterocyclic dihydropyran ring) with two fluorine atoms at positions 5 and 7 and a ketone functional group at position 4.

Chemical Reactions Analysis

5,7-Difluorochroman-4-one can undergo an asymmetric reduction reaction to produce ®-5,7-difluorochroman-4-ol. This reaction is catalyzed by ketoreductase in the presence of a coenzyme.

Physical And Chemical Properties Analysis

5,7-Difluorochroman-4-one is a solid at room temperature. It has a molecular weight of 184.14 and a boiling point of 283°C at 760 mmHg. The compound has a density of 1.4±0.1 g/cm3 and a flash point of 121.1±22.2 °C.

Scientific Research Applications

• Pharmaceutical Research

  • Chroman-4-one derivatives, including “5,7-Difluorochroman-4-one”, are a significant structural entity in the class of oxygen-containing heterocycles. They act as a major building block in a large class of medicinal compounds.
  • These compounds exhibit a broad variety of remarkable biological and pharmaceutical activities. Several studies have been performed to improve the methodologies of 4-chromanone-derived compounds.
  • The specific methods of application or experimental procedures vary widely depending on the specific research context and the type of medicinal compound being synthesized.
  • The outcomes of these studies have led to the development of a variety of medicinal compounds with diverse biological and pharmaceutical activities.

• Synthesis of Chiral Drugs

  • “5,7-Difluorochroman-4-one” has been used in the synthesis of chiral drugs.
  • The specific methods of application or experimental procedures would depend on the specific chiral drug being synthesized.
  • The outcomes of these studies have contributed to the development of new chiral drugs.

• Synthesis of Agrochemicals

  • “5,7-Difluorochroman-4-one” has also been used in the synthesis of agrochemicals.
  • The specific methods of application or experimental procedures would depend on the specific agrochemical being synthesized.
  • The outcomes of these studies have contributed to the development of new agrochemicals.

• Synthesis of Fluorinated Compounds

  • “5,7-Difluorochroman-4-one” has been used in the synthesis of fluorinated compounds.
  • The specific methods of application or experimental procedures would depend on the specific fluorinated compound being synthesized.
  • The outcomes of these studies have contributed to the development of new fluorinated compounds.

• Preparation of Tetrazolinone Compounds

  • “5,7-Difluorochroman-4-one” is used as a reagent in the preparation of tetrazolinone compounds.
  • These compounds are used as pest control agents.
  • The specific methods of application or experimental procedures would depend on the specific tetrazolinone compound being synthesized.
  • The outcomes of these studies have contributed to the development of new pest control agents.

• Cosmetic Preparations

  • Chromanone derivatives, including “5,7-Difluorochroman-4-one”, are used as active compounds in cosmetic preparations.
  • They are used for the care, improvement, and refreshment of the texture of the skin and hairs, and for the treatment of skin as well as hair-related defects like inflammation, allergies, or wound healing process.
  • The specific methods of application or experimental procedures would depend on the specific cosmetic preparation.
  • The outcomes of these studies have contributed to the development of new cosmetic preparations.

• Preparation of Tetrazolinone Compounds

  • “5,7-Difluorochroman-4-one” is used as a reagent in the preparation of tetrazolinone compounds.
  • These compounds are used as pest control agents.
  • The specific methods of application or experimental procedures would depend on the specific tetrazolinone compound being synthesized.
  • The outcomes of these studies have contributed to the development of new pest control agents.

• Research and Development

  • “5,7-Difluorochroman-4-one” is used for R&D purposes.
  • The specific methods of application or experimental procedures would depend on the specific research context.
  • The outcomes of these studies have contributed to the development of new compounds and methodologies.

Safety And Hazards

The safety information for 5,7-Difluorochroman-4-one indicates that it should be stored in a dry room at normal temperature. It is recommended to avoid dust formation, breathing mist, gas, or vapors, and contact with skin and eyes. The use of personal protective equipment and chemical impermeable gloves is advised.

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