850220-97-2 | 6-BroMo-2-fluoro-pyridin-3-aMine

CAS:850220-97-2 | 6-BroMo-2-fluoro-pyridin-3-aMine,Description

“6-Bromo-2-fluoropyridin-3-amine” is a chemical compound with the CAS Number: 850220-97-2. It has a molecular weight of 191 and its IUPAC name is 6-bromo-2-fluoro-3-pyridinamine.

Molecular Structure Analysis

The InChI code for “6-Bromo-2-fluoropyridin-3-amine” is 1S/C5H4BrFN2/c6-4-2-1-3 (8)5 (7)9-4/h1-2H,8H2. This code provides a specific string of characters that represents the molecular structure of the compound.

Scientific Research Applications

Chemoselective Functionalization

The compound's utility in chemoselective functionalization is highlighted by Stroup et al. (2007) who describe the selective substitution processes in 5-bromo-2-chloro-3-fluoropyridine. This research emphasizes the compound's potential in synthesizing specific substitution products through catalytic amination, revealing its importance in organic synthesis and chemical manufacturing (Stroup et al., 2007).

Radiosynthesis Applications

Pauton et al. (2019) explore the compound's role in the radiosynthesis of 2-amino-5-[18F]fluoropyridines. This involves a palladium-catalyzed reaction, signifying the compound’s potential in creating radio-labelled substances for medical imaging and diagnostic purposes (Pauton et al., 2019).

Ligand Synthesis

Benhamou et al. (2011) discuss the synthesis of complex ligands involving 6-bromo-2-fluoropyridin-3-amine. This synthesis demonstrates the compound's role in forming intricate chemical structures, which could be crucial in coordination chemistry and catalysis (Benhamou et al., 2011).

Synthesis of Disubstituted Fluoropyridines

Sutherland and Gallagher (2003) illustrate the compound’s application in synthesizing disubstituted fluoropyridines via Suzuki reactions. This underscores its importance in the creation of diverse organic compounds, potentially useful in pharmaceuticals and materials science (Sutherland & Gallagher, 2003).

Antimalarial Activity

Lin et al. (1990) investigate derivatives of the compound for their antimalarial activity. This research indicates the potential pharmaceutical applications of 6-Bromo-2-fluoropyridin-3-amine in developing new treatments for malaria (Lin et al., 1990).

Catalyst in Amination

Ji et al. (2003) explore the use of 6-Bromo-2-fluoropyridin-3-amine in catalyzing amination reactions. This underlines its utility in facilitating chemical reactions, particularly in the synthesis of complex organic molecules (Ji et al., 2003).

Safety And Hazards

The compound has been assigned the GHS07 pictogram. The hazard statements associated with it are H302+H312+H332;H315;H319;H335, indicating that it can be harmful if swallowed, in contact with skin, or if inhaled, and it can cause skin and eye irritation and may cause respiratory irritation. The precautionary statements include P301+P312;P302+P352;P305+P351+P338, advising on measures to take in case of exposure.

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