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Purchase CAS:876617-25-3 | (R)-1-BOC-3-FLUORO PYRROLIDINE,view related peer-reviewed papers,technical documents,similar products,MSDS & more.This would involve providing a detailed overview of the compound, including its molecular formula, molecular weight, and structural formula. The compound’s role or use in various applications or industries would also be discussed....
This would involve providing a detailed overview of the compound, including its molecular formula, molecular weight, and structural formula. The compound’s role or use in various applications or industries would also be discussed.
This would involve a detailed discussion of how the compound is synthesized, including the starting materials, reaction conditions, and the overall reaction mechanism.
This would involve discussing the molecular structure of the compound, including its stereochemistry if applicable. Techniques such as X-ray crystallography, NMR spectroscopy, and mass spectrometry are often used to determine the structure of a compound.
This would involve discussing the chemical reactions that the compound undergoes. This could include its reactivity with other compounds, its stability under various conditions, and any notable reaction mechanisms.
This would involve discussing the physical and chemical properties of the compound, such as its melting point, boiling point, solubility, and reactivity.
The compound has been utilized in the identification of enantiomers of related compounds. Procopiou et al. (2016) detailed the determination of the absolute configuration of enantiomers of a related compound, N-CBZ-3-fluoropyrrolidine-3-methanol, by vibrational circular dichroism. This process involved exchanging the CBZ protecting group with Boc and further chemical synthesis steps, establishing the (R)-configuration of the enantiomer (Procopiou et al., 2016).
(R)-1-Boc-3-fluoropyrrolidine has been used in the synthesis of fluorinated azaheterocycles, which are important as bifunctional building blocks for pharmaceutical compounds. Verniest et al. (2010) described an efficient synthesis of fluorinated piperidines and pyrrolidines, highlighting the compound's significance in medicinal chemistry (Verniest et al., 2010).
In the field of pharmaceutical research, the compound has been studied for its potential in metabolic activation. Xu et al. (2004) evaluated two dipeptidyl peptidase-IV inhibitor analogs containing a fluoropyrrolidine moiety, demonstrating the compound's role in metabolic activation processes (Xu et al., 2004).
The compound is pivotal in synthesizing intermediates for medicinal chemistry applications. Singh and Umemoto (2011) synthesized N-protected fluoropyrrolidine derivatives, showcasing its utility in creating compounds for medicinal purposes (Singh & Umemoto, 2011).
It's also used in fluoroamination processes, as demonstrated by Combettes et al. (2012), where the intramolecular fluoroamination of homoallylic amines led to the formation of 3-fluoropyrrolidines (Combettes et al., 2012).
(R)-1-Boc-3-fluoropyrrolidine is also instrumental in conformational analysis of fluorinated compounds. Studies by Combettes et al. (2012) on 3-fluoropyrrolidines used scalar couplings and heteronuclear NOEs to investigate ring conformations, highlighting the compound's importance in structural chemistry (Combettes et al., 2012).
The compound has been pivotal in the development of new fluorinated beta-amino acids, which have high potential as building blocks in medicinal chemistry. Van Hende et al. (2009) demonstrated this through the synthesis of 3-fluoroazetidine-3-carboxylic acid (Van Hende et al., 2009).
This would involve discussing any known safety concerns or hazards associated with the compound. This could include its toxicity, flammability, and any precautions that need to be taken when handling it.
This would involve discussing potential future research directions or applications for the compound. This could be based on current research trends, identified gaps in the literature, or novel applications for the compound.
For a specific compound like “®-1-Boc-3-fluoropyrrolidine”, you would need to consult the relevant scientific literature or databases to gather this information. Please note that not all compounds will have information available for all of these categories, especially if they are not widely studied. It’s always important to refer to the most up-to-date and reliable sources when conducting such an analysis.
Product Name: | (R)-1-BOC-3-FLUORO PYRROLIDINE |
Synonyms: | (R)-1-BOC-3-FLUORO PYRROLIDINE;(3R)-3-Fluoropyrrolidine, N-BOC protected;tert-Butyl (3R)-3-fluoropyrrolidine-1-carboxylate;(R)-tert-butyl 3-fluoropyrrolidine-1-carboxylate;(S)-tert-butyl 3-fluoropyrrolidine-1-carboxylate;(3R)-3-Fluoro-1-Pyrrolidinecarboxylic acid tert-butyl ester;(R)-(-)-1-Boc-3-fluoropyrrolid;1-Pyrrolidinecarboxylic acid, 3-fluoro-, 1,1-dimethylethyl ester, (3R)- |
CAS: | 876617-25-3 |
MF: | C9H16FNO2 |
MW: | 189.23 |
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Product Categories: | |
Mol File: | 876617-25-3.mol |
(R)-1-BOC-3-FLUORO PYRROLIDINE Chemical Properties |
Boiling point | 230℃ |
density | 1.08 |
Fp | 93℃ |
refractive index | 1.4420 |
storage temp. | 2-8°C |
pka | -3.60±0.40(Predicted) |
form | Liquid |
color | Colorless to pale yellow |
Sensitive | Moisture Sensitive |
CAS DataBase Reference | 876617-25-3 |