886050-51-7 | 2-(Trifluoromethoxy)ethylamine hydrochloride

CAS:886050-51-7 | 2-(Trifluoromethoxy)ethylamine hydrochloride ,Description

2-(Trifluoromethoxy)ethylamine hydrochloride, also known as TFMEA-HCl, is a powerful and versatile reagent in synthetic organic chemistry. It is a highly reactive compound, with a wide range of applications in both industrial and academic research. TFMEA-HCl is used in the synthesis of a variety of compounds, including pharmaceuticals, polymers, and biocatalysts. It is also used in the synthesis of complex molecules and bioconjugates.
 

Scientific Research Applications

• Preformulation Studies: A study conducted by Morita et al. (1995) investigated the preformulation of a 2-(3,4-dimethoxyphenyl)ethylamine derivative. This research is crucial for understanding the properties of such compounds, including 2-(Trifluoromethoxy)ethylamine hydrochloride, during the early stages of drug development, especially for oral administration (Morita et al., 1995).
• Synthesis for Tracer Compounds: Hong et al. (2008) described the synthesis of tritium-labeled [1,2-3H]ethylamine hydrochloride, used in the production of [N-ethyl-1,2-3H]apadenoson, an adenosine A2a receptor agonist. This kind of research is valuable for creating tracer compounds for scientific studies, including those involving 2-(Trifluoromethoxy)ethylamine hydrochloride (Hong et al., 2008) .
• Corrosion Inhibition: Zhang et al. (2015) examined the use of halogen-substituted imidazoline derivatives, including a compound similar to 2-(Trifluoromethoxy)ethylamine hydrochloride, as corrosion inhibitors for mild steel in acidic solutions. This highlights a potential application of 2-(Trifluoromethoxy)ethylamine hydrochloride in industrial settings for protecting metals from corrosion (Zhang et al., 2015).
• Chitosan Hydrogel Cross-linking: A study by Karimi et al. (2018) explored the use of tris(2-(2-formylphenoxy)ethyl)amine, a compound structurally related to 2-(Trifluoromethoxy)ethylamine hydrochloride, as a cross-linker in the formation of chitosan hydrogels. These hydrogels have potential applications in drug delivery and other biomedical fields (Karimi et al., 2018).
• Antibacterial Activity: In the study by Xie et al. (2007), ethylamine hydroxyethyl chitosan, synthesized from chitosan and chloroethylamine hydrochloride (structurally similar to 2-(Trifluoromethoxy)ethylamine hydrochloride), was shown to have antibacterial activities against Escherichia coli. This suggests potential antibacterial applications for similar compounds (Xie et al., 2007).

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