942493-23-4 | 6-Chloro-7-fluoro-1H-indole-2,3-dione

CAS:942493-23-4 | 6-Chloro-7-fluoro-1H-indole-2,3-dione,Description

6-Chloro-7-fluoroindoline-2,3-dione is a chemical compound with the molecular formula C8H3ClFNO2 and a molecular weight of 199.57. It is a solid substance at room temperature.

Molecular Structure Analysis

The InChI code for 6-Chloro-7-fluoroindoline-2,3-dione is 1S/C8H3ClFNO2/c9-4-2-1-3-6 (5 (4)10)11-8 (13)7 (3)12/h1-2H, (H,11,12,13) and the InChI key is KPIXRLPJNJURAJ-UHFFFAOYSA-N.

Physical And Chemical Properties Analysis

6-Chloro-7-fluoroindoline-2,3-dione is a solid at room temperature. It has a molecular weight of 199.57. The compound’s InChI code is 1S/C8H3ClFNO2/c9-4-2-1-3-6 (5 (4)10)11-8 (13)7 (3)12/h1-2H, (H,11,12,13) and the InChI key is KPIXRLPJNJURAJ-UHFFFAOYSA-N.

Scientific Research Applications

• Specific Scientific Field : Organic Chemistry.
• Summary of the Application : 6-Chloro-7-fluoroindoline-2,3-dione is used in the synthesis of novel fluorinated indole derivatives. Fluorinated indoles have received considerable attention because the incorporation of fluorine into a target molecule can influence reactivity, selectivity, and biological activity.
• Methods of Application or Experimental Procedures : The synthesis of these novel fluorinated indole derivatives is achieved by reacting 5-fluoroindoline-2,3-dione with various anilines. This reaction is conducted using readily available substrates under microwave irradiation, which allows for full reaction control, excellent product yields, shorter reaction time, and an eco-friendly procedure.
• Summary of Results or Outcomes : The reaction yields products in good to excellent yields (64–92%) within short periods of 9–15 minutes.

Safety And Hazards

The safety information for 6-Chloro-7-fluoroindoline-2,3-dione indicates that it has the GHS07 pictogram. The hazard statements are H302-H315-H319-H335, and the precautionary statements are P261-P280-P301+P312-P302+P352-P305+P351+P338. The safety data sheet suggests avoiding dust formation, breathing mist, gas or vapours, and contact with skin and eyes.

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