951127-25-6 | CPo3604-01

CAS:951127-25-6 | CPo3604-01,Description

The compound contains a tert-butyl group, which is a branched alkyl group known for its unique reactivity pattern. It also contains a 2,5-difluorophenyl group, which is a type of aromatic ring with fluorine substituents, and a tetrahydro-2H-pyran ring, which is a type of heterocyclic compound.

Molecular Structure Analysis

The molecular structure of this compound would be quite complex, with several different functional groups and rings. The tert-butyl group would likely add steric bulk, while the 2,5-difluorophenyl group could contribute to the compound’s electronic properties.

Chemical Reactions Analysis

The reactivity of this compound would depend on the specific conditions and reagents used. The tert-butyl group is known for its unique reactivity pattern, and the presence of the aromatic ring and the pyran ring could also influence the compound’s reactivity.

Physical And Chemical Properties Analysis

The physical and chemical properties of this compound would depend on its specific structure and the presence of various functional groups. For example, the tert-butyl group could influence the compound’s solubility and boiling point.

Scientific Research Applications

• Synthesis of Protease Inhibitors : Ghosh, Cárdenas, and Brindisi (2017) describe the enantioselective synthesis of tert-butyl carbamates, including a potent β-secretase inhibitor. This application is significant in the development of protease inhibitors, which have therapeutic potential in treating diseases like Alzheimer's (Ghosh, A. K., Cárdenas, E. L., & Brindisi, M., 2017).
• Diels-Alder Cycloadditions : Omar, Santucci, and Afarinkia (2022) investigated the use of tert-butyl carbamate as a “chameleon” diene in Diels-Alder cycloadditions, showcasing its versatility in reacting with different dienophiles. This has implications for the synthesis of complex organic molecules (Omar, Y. M., Santucci, G., & Afarinkia, K., 2022).
• Conformational Studies : Chmielewski et al. (1982) explored the NMR spectra of tert-butyl 2-methoxy-5,6-dihydro-2H-pyran derivatives, providing valuable information on their molecular conformation. Understanding such conformations is essential for their application in synthesis and drug design (Chmielewski, M., Jurczak, J., Zamojski, A., & Adamowicz, H., 1982).
• Photocatalyzed Amination : Wang et al. (2022) demonstrated a photoredox-catalyzed amination process using tert-butyl carbamate, leading to the synthesis of 3-aminochromones. This method could be used to construct a variety of complex molecules, expanding the utility of photoredox chemistry (Wang, Z.-W., Zheng, Y., Qian, Y.-E., Guan, J., Lu, W., Yuan, C.-P., Xiao, J.-A., Chen, K., Xiang, H., & Yang, H., 2022).
• Synthesis of NK1 Receptor Antagonist : Sugawara and Hashiyama (2007) applied tert-butyl carbamate in the synthesis of NK1 receptor antagonist, highlighting its role in the production of pharmaceuticals (Sugawara, K., & Hashiyama, T., 2007).
• Crystal Structures Involving Hydrogen and Halogen Bonds : Baillargeon et al. (2017) studied the crystal structures of tert-butyl carbamate derivatives, providing insights into molecular interactions crucial for material science and crystallography (Baillargeon, P., Rahem, T., Caron-Duval, É., Tremblay, J., Fortin, C., Blais, É., Fan, V., Fortin, D., & Dory, Y., 2017).
• Biocatalytic Procedures in Industrial Synthesis : Troiani, Cluzeau, and Časar (2011) described a chemoselective biocatalytic procedure using tert-butyl carbamate for synthesizing a key lactonized statin side chain intermediate, demonstrating its potential in industrial pharmaceutical production (Troiani, V., Cluzeau, J., & Časar, Z., 2011).
• Strong and Weak Hydrogen Bonds in Carbamate Derivatives : Das et al. (2016) synthesized carbamate derivatives, including tert-butyl carbamate, and analyzed their crystal structures. This study contributes to understanding molecular assemblies and interactions in solid-state chemistry (Das, U., Chattopadhyay, B., Hazra, D., Sureshbabu, V., & Mukherjee, A. K., 2016).

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