993-95-3 | 1,1,2,3,3,3-Hexafluoropropyl 2,2,2-trifluoroethyl ether

CAS:993-95-3 | 1,1,2,3,3,3-Hexafluoropropyl 2,2,2-trifluoroethyl ether ,Description

1,1,2,3,3,3-Hexafluoropropyl 2,2,2-trifluoroethyl ether, also known as HFPT, is an organic compound with a wide range of applications in the scientific research field. It is a colorless liquid with a low boiling point and low volatility, making it an ideal solvent for a variety of applications. HFPT is a non-flammable, non-toxic, and non-corrosive compound, making it a safe and versatile compound for laboratory use. HFPT is also known for its low vapor pressure and low surface tension, making it a useful solvent for a variety of organic compounds. 
 

Scientific Research Applications

Vapor Pressure and Activity Coefficients

Fukuchi et al. (2004) conducted a study to measure the vapor pressures of fluoroethers, including 1,1,2,3,3,3-hexafluoropropyl 2,2,2-trifluoroethyl ether, at various temperatures using a gas stripping method. They also measured the infinite dilution activity coefficients of these fluoroethers in hexadecane or water, and the results were correlated using the modified ASOG method Fukuchi et al., 2004.

Vapor-Liquid Equilibria

Hiaki et al. (2002) explored the isobaric vapor-liquid equilibria (VLE) for binary systems containing 1,1,2,3,3,3-hexafluoropropyl 2,2,2-trifluoroethyl ether with several organic solvents, demonstrating minimum boiling azeotropes in these systems Hiaki et al., 2002 .

Role in Hypervalent Iodine Chemistry

Dohi et al. (2010) discussed the use of fluoroalcohols, such as 1,1,1,3,3,3-hexafluoroisopropanol, as solvents in hypervalent iodine-mediated phenolic oxidations. These solvents have been shown to stabilize reactive cationic intermediates, leading to breakthroughs in hypervalent iodine chemistry and synthetic applications Dohi et al., 2010.

Application in Lithium-Sulfur Batteries

Lu et al. (2016) investigated the addition of 1,1,2,2-tetrafluoroethyl 2,2,2-trifluoroethyl ether to a solvate ionic liquid electrolyte for lithium-sulfur batteries. This fluorinated ether improved the cycle and rate capability of the batteries Lu et al., 2016.

As a Leaving Group in Organic Synthesis

Fisher et al. (2018) described the use of the 2,2,2-trifluoroethoxy group as an alternative leaving group in organic synthesis, particularly for hydrolytically unstable heteroaryl chlorides. This group improves shelf stability while maintaining reactivity Fisher et al., 2018.

Photocatalysis in Organic Reactions

Huang et al. (2015) demonstrated the use of 1,1,1-trifluoro-2-iodoethane in visible-light-induced photoredox reactions with alkylalkenes and silyl enol ethers, introducing a 2,2,2-trifluoroethyl group and an iodine atom to the double bond of alkenes Huang et al., 2015.

As a Protecting Group in Organic Synthesis

Yang et al. (2013) discussed the introduction and removal of trifluoroethyl (TFE) ether as a protecting group in organic chemistry, highlighting its strategic application in the total synthesis of vinigrol Yang et al., 2013.

Role in Polymer Science

Jang et al. (2007) studied the effect of trifluoromethyl (CF3) groups and ether groups on the optical and dielectric properties of fluorinated polyimide thin films, indicating the influence of these groups on material properties Jang et al., 2007.

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