99627-05-1 | 3,4,5-Trifluorophenol

CAS:99627-05-1 | 3,4,5-Trifluorophenol ,Description

3,4,5-Trifluorophenol (3,4,5-TFP) is a synthetic organic compound that has been used in a variety of laboratory experiments and scientific research applications. It is an aromatic hydroxy compound with a molecular formula of C6H3F3O. 3,4,5-TFP is a widely used reagent in organic synthesis due to its ability to undergo a variety of reactions. It is also used in the production of pharmaceuticals, dyes, and other chemicals.
 

Scientific Research Applications

Catalytic Activity Enhancement

Tris(3,4,5-trifluorophenyl)borane, a compound related to 3,4,5-trifluorophenol, has been studied for its catalytic activity. It is particularly effective in hydroboration reactions of unsaturated substrates. This compound shows enhanced activity under microwave irradiation, effectively hydroborating alkenes and alkynes in good yields (Carden et al., 2019).

Functionalization of Fluorophenols

Research has explored the functionalization of various difluorophenols and trifluorophenols, including 3,4,5-trifluorophenol, into hydroxybenzoic acids. This study demonstrates the potential of the organometallic approach for synthesizing a diverse range of compounds (Marzi et al., 2004).

Spectroscopic Applications

Fluorinated phenols, such as 3,4,5-trifluorophenol, have been investigated as pH-sensitive probes in mixed liposomal systems. The study highlights their usefulness in understanding probe–liposome interactions across various pH levels, which is crucial for biomedical research and diagnostics (Gasbarri & Angelini, 2014).

Optical and Dielectric Properties

The effects of internal linkage groups of fluorinated diamine on optical and dielectric properties of polyimide thin films have been studied, showing the influence of trifluoromethyl groups on the properties of these materials. This research has implications for developing advanced materials with specific optical and electronic characteristics (Jang et al., 2007).

Organometallic Framework Design

A study on a nanocage-based InIII{TbIII}2-organic framework featuring lotus-shaped channels has utilized fluorinated phenyl groups, demonstrating their application in creating frameworks for CO2 fixation and I2 capture. This has significant potential in environmental applications and industrial processes (Chen et al., 2020).

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